News from the Genetics, Epigenetics and Biology of Sarcomas Team



November 2021

We are welcoming Dr Hélène Vanacker, MD, who is starting her PhD in our lab: 
"DeepCan: Development of deep-Learning approaches from RNA-seq data for prognostic and theranostic prediction in cancers, correlated with novel genomic factors"

April 2021

We are hiring a post-doc for a 18months position. See the description here

April 2021

We finally moved! Not far, just into another building of the CRCL ;-) You can now find us on the second floor of the "Cheney D" building. More space + new neighbors = more science!

January 2021

Happy new year!!!! 
On the 1st of January 2021 we became the CRCL's "Genetics, Epigenetics and Biology of Sarcomas" (aka GEBS) Team (with a brand new logo!:-)

November 2020

Congratulations to Mehdi Brahmi who defended his PhD thesis: "Analyses transcriptomiques et fonctionnelles des anomalies moléculaires récurrentes des sarcomes du stroma endométrial" on the 10th of November! Well done Mehdi!

October 2020

Second paper on novel SRF fusions :-)
After new SRF Fusions in well-differentiated RMS, we are publishing the description of novel SRF fusions in perivalscular tumors. Congrats Marie!

SRF Fusions Other Than With RELA Expand the Molecular
Definition of SRF-fused Perivascular Tumors. Am J Surg Pathol 2020,  https://doi.org/10.1097/PAS.0000000000001546 

September 2020

Proud to share our latest publication on the molecular classification of Endometrial sarcomas :
Molecular classification of endometrial stromal sarcomas using RNA sequencing defines nosological and prognostic subgroups with different natural history. Cancers 2020, 12(9), 2604; https://doi.org/10.3390/cancers12092604

May 2020

Back to the lab! At least 2 months lost because of a virus...but everybody is going well ;-) 

March 2020
Due to the coronavirus pandemic, the lab is closing for few weeks ;-(
 Despite these difficult times, papers are still coming out, look at our latest publication:

SRF-FOXO1 and SRF-NCOA1 fusion genes delineate a distinctive subset of well differentiated rhabdomyoblastic tumor. Am J Surg Pathol. 44(5):607-616. doi:10.1097/PAS.0000000000001464

January 2020

We welcome Amandine, a Master 2 student who will investigate the function(s) of the HEY1-NCOA2 fusion protein. 

Best wishes to Marine. Thank you for all you've done, (especially the PDX derived cell lines ;-)

!!! HAPPY NEW YEAR !!!

September 2019

Welcome to Quentin, Master 2 student in bioinformatics !

Good luck to Yanis Zekri who will start his PhD in F. Flamant's lab (IGFL) and to Ophélie Arnaud who now lives new adventures in Paris area !

August 2019 

We are hiring a Engineer in Bioinformatics ! More info here: Engineer in Bioinformatics 

Our last publication "A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation" published in Modern Pathology is out! https://www.nature.com/articles/s41379-019-0323-8

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